San Francisco to Cartagena

This is a business class deal to Cartagena from San Francisco on American for Dec 5, 2026 – Dec 11, 2026.

Priced at $937 round trip. The route covers 6,905 miles round trip.

Cartagena, on Colombia’s Caribbean coast, is one of South America’s most atmospheric destinations, blending colonial history, seaside energy, and a distinctly warm, tropical pace. Its UNESCO-listed old town is a major draw: inside the thick stone walls, narrow streets, flower-draped balconies, shaded plazas, and restored mansions create a setting that feels both historic and alive. Beyond the center, neighborhoods such as Getsemaní offer a more bohemian side of the city, with street art, live music, and an easygoing nightlife scene, while Bocagrande provides a modern contrast with high-rise hotels and beach access.

The best time to visit is during the drier months, typically from December to April, when sunny weather is most reliable for sightseeing and coastal outings. Cartagena’s appeal also lies in its food and culture: expect Caribbean-influenced seafood, coconut rice, fried fish, arepas, and fresh tropical fruit, along with strong Afro-Caribbean traditions visible in music, dance, and festivals. For travelers considering a trip, Cartagena offers a rare combination of history, color, and coastal charm, making it especially compelling for those who want culture and relaxation in one easy-to-enjoy destination.